When a patient is treated with carbidopa/levodopa over time, symptoms may reemerge before the next scheduled dose. This is called symptom reemergence due to "wearing-off."

While medications such as carbidopa/levodopa initially provide control, over time you may see changes in the way carbidopa/levodopa controls your symptoms. At times, you may become very slow and stiff, have difficulty dressing or walking, or see a reemergence of tremor.

If you take carbidopa/levodopa for Parkinson's disease (PD), you may find that your symptoms begin to come back before the next scheduled dose of carbidopa/levodopa.

This change is called "wearing-off."

Inform your health care professional (HCP) if you notice symptom reemergence. This is due to medication "wearing-off," and it may mean it's time to adjust or change your medication. Consult your HCP before making any change to your medication regimen. Consistent communication with HCPs is essential for managing your symptoms as they surface.

You may think about holding back information from your HCP out of fear that it means your PD is getting worse.

Don't. Your HCP needs an accurate idea of your symptoms in order to help better assess your treatment options or optimize your medications.